Summit Provider


WellSpan Endocrinology

12 St Paul Dr Suite 210
Chambersburg, PA 17201
Phone:(717) 217-6820
Fax:(717) 217-6942

WellSpan Endocrinology

354 Alexander Spring Road Suite 3
Carlisle, PA 17015
Phone:(717) 217-6820
Fax:(717) 217-6942





Medical School: 
Michigan State University College of Osteopathic Medicin
Henry Ford Health System
William Beaumont Hospital
Penn State Hershey Medical Center
American Board of Internal Medicine Endocrinology



Dr. Signori joined Summit Endocrinology in August, 2012. She specializes in the treatment of disorders of the endocrine system. This includes diabetes, thyroid disorders, osteoporosis, and disorders of the pituitary and adrenal glands.

She obtained her Bachelors degree and Masters of Public Health from the University of Michigan in Ann Arbor, Michigan. She obtained her medical degree from Michigan State University College of Osteopathic Medicine in East Lansing, Michigan. She received her residency training at William Beaumont Hospital in Royal Oak, Michigan in Internal Medicine. She finished her endocrinology fellowship at Penn State Milton S. Hershey Medical Center.

She has presented her work at national meetings and published several papers in prominent medical journals. Her most recent publications include:

  • Sandhu N., Schetter S., Liao J., Hartman T., Richie J., McGinley J., Thompson H., Prokopczyk B., DuBrock C., Signori C., Hamilton C., Calcagnotto A., Trushin N., Aliaga C., Demers L., El-Bayoumy K., Manni A. Influence of obesity on breast density reduction by omega-3 fatty acids: Evidence from a randomized clinical trial. Cancer Prevention Research
  • Signori C., DuBrock C., Richie J.P. Jr., Prokopczyk B., Demers L., Hamilton C., Hartman, T., Liao J., El-Bayoumy K., Manni A. Administration of omega-3 fatty acids and raloxifene to women at high risk of breast cancer: Interim feasibility and biomarkers analysis from a clinical trial. Accepted for publication in European Journal of Nutrition May 10, 2012.
  • Signori C., El-bayoumy K., Russo J., Thompson H., Richie J., Hartman T. Manni A. Chemoprevention of breast cancer by fish oil in preclinical models: Trials and tribulation. Cancer Research. 2011;71:6091-6096.
  • Signori C., Zalesin K.C., Franklin B., Miller W.L., McCullough P.A. Effect on vitamin D and secondary hyperparathyroidism. Obesity Surgery. 2010 July; (20)7: 949-952.

Q: What led you to work in your particular field of medicine?

Answer: Endocrinology is interesting and makes sense once you understand the basic concepts.  Also, although people with endocrine diseases still can suffer, it is a field of medicine where we have treatment options for most things and rarely am I seeing hopeless cases so I feel like I can really help people in this field.

Q: What drew you to begin practicing in the Franklin County area?

Answer:  I love practicing in Franklin County.  It is a beautiful part of  Pennsylvania and the people are very special - in general very polite and appreciative.

Q: What would you say is a common misconception about your particular field of medicine?

Answer: First, that “natural” supplements are safer than prescribed medications. That is often not the case.  Second, that endocrinology is the study of "hormones."  We can evaluate the different endocrine hormones: pituitary, thyroid, adrenal but being able to measure and replace exact levels of female hormones to improve sense of wellbeing is not part of what we can do.

Q: What are you most looking forward to about working in Franklin County?

Answer:  Helping the community have easier access to an endocrinologist.

Q: What hobbies or interests do you enjoy outside of your career?

Answer:  I am a mom so I enjoy being with my family and taking care of them.  Also, I am just learning how to fly fish which I do with my brothers in the beautiful creeks we have in Pennsylvania.